526 次均相時(shí)間分辨熒光共振能量轉(zhuǎn)移技術(shù)的原理、優(yōu)勢、應(yīng)用與進(jìn)展 2025-12-16
一、技術(shù)概述與核心價(jià)值均相時(shí)間分辨熒光共振能量轉(zhuǎn)移(Time-Resolved Fluorescence Resonance Energy Transfer, TR-FRET)是一種將時(shí)間分辨熒光技術(shù)與Förster共振能量轉(zhuǎn)移原理相結(jié)合的高靈
624 次機(jī)械應(yīng)力經(jīng)激活BDKRB1-ERK軸促進(jìn)鈣內(nèi)流和肺泡上皮細(xì)胞的生長 2025-11-7
Mechanical stress facilitates calcium influx and growth of alveolar epithelial cells via activation of the BDKRB1/Ca2+/CaMKII/MEK1/ERK axisKeywords: Alveolar epithelial cells, Mech
670 次紊亂的血流經(jīng)Frizzled-4-β-catenin依賴性通路增加內(nèi)皮炎癥和通透性 2025-11-7
Disturbed flow increases endothelial inflammation and permeability via a Frizzled-4-β-catenin-dependent pathwayKeywords: Mechanotransduction, Inflammation, Orbital shaker, Ath
975 次TR-FRET/FRET實(shí)驗(yàn)常見問題和解決方案及其在藥物研發(fā)中的應(yīng)用 2025-10-20
FRET(Fluorescence Resonance Energy Transfer,熒光共振能量轉(zhuǎn)移)實(shí)驗(yàn)是一種基于兩個(gè)熒光分子之間距離依賴性能量傳遞的檢測技術(shù),常用于研究生物大分子之間的相互作用或構(gòu)象變化。TR-FRET(T
781 次機(jī)械力應(yīng)力對人牙周膜細(xì)胞炎癥反應(yīng)的影響 2025-9-16
Effect of Mechanical Force Stress on the Inflammatory Response in Human Periodontal Ligament CellsKeywords: Bone remodelling, Cytokines, Mechanical stress, Mesenchymal stem cells,
757 次CircPRKD3/miR-6783-3p 響應(yīng)機(jī)械力促進(jìn)牽張狀態(tài)牙周膜干細(xì)胞成骨 2025-9-3
CircPRKD3/miR-6783-3p responds to mechanical force to facilitate the osteogenesis of stretched periodontal ligament stem cellsKeywords: CircPRKD3, miR-6783-3p, ceRNAs, PDLSCs, Mech